please explain where these 6NADH2, 2FADH2 and 2ATP molecules are formed in ''Krebs cycle'' and how??
As you can see from the image,
FORMATION OF 6NADH2
1. Decarboxylation (removal of carbon dioxide) from isocitrate to form alpha-ketoglutarate
2. Decarboxylation of alpha-ketoglutarate to succinyl CoA
3.Conversion of malate to oxaloacetate.
These three reaction occurs twice so produce 6 NADH2 as two pyruvate molecules are formed from one molecule of glucose.
FORMATION OF 2FADH2
Conversion of Succinate to Fumarate. This reaction also occurs twice so produces two molecules.
FORMATION OF 2ATP
When Succinyl CoA gets converted to Succinate it produces a molecule of GTP. This GTP gets converted to form ATP. This reaction also occurs twice so produces two molecules of ATP
See first the cycle is repeated 2 times as 1 glucose molecule produces two molecules of pyruvate or pyruvic acid.
1st NAD TO NADH+H+ - ISO CITRIC ACID TO OXALOSUCCINATE
2ND - ALPHA KETOGLUTARIC ACID TO SUCCINYL CO ENZYME A
3RD- MALATE TO OXALOACETATE
ATP PRODUCED FROM GTP I.E guanosine triphosphate which later on gets converted to the adenosine tri phosphate (ATP) WHICH IS SYNTHESIZED FROM SUCCINYL COENZYME A TO SUCCINATE